Nowadays, people visit their physicians for issues related to chronic pain. Some people use CBD or cannabidiol oil to manage this pain, and it has proven to be effective. This oil contains CBD, one of the most important naturally present chemical compounds in the cannabis plant. This oil is safe to use as it does not induce the feeling of intoxication. Those feelings relate to another cannabinoid called THC.

The ongoing research shows that CBD oil has a lot of potential to influence pain management. It is also known to be effective in reducing inflammation and other health-related problems. It is possibly a better alternative for people with chronic pain, depending upon habit-forming and risky drugs like opioids.

CBD oil has a lot of potential to influence pain


The endocannabinoid system (ECS) present in the central and peripheral nervous systems throughout the body has two main receptors, namely the CB1 and CB2 receptors. CBD interacts specifically with the CB2 receptors and gives rise to its therapeutic reactions like pain management. This interaction also negates the mind-altering effects of the interactions between the CB1 receptors and THC. To back-up these claims, you can read stories about CBD and how it helped people to manage pain.


CBD relieves neuropathic pain, nociceptive pain, and other types of pain, which are hard to categorize.

The Johns Hopkins University conducted research on the effects of non psychoactive cannabinoids on rat spinal cord slices. It was seen that it significantly suppressed chronic inflammation and neuropathic pain without causing analgesic tolerance. Neuropathic pain mostly happens due to the glutaminergic system, a major excitatory neuronal pathway. Glutamate is a neurotransmitter that turns on the neurons, which is good sometimes.

Specialists at Dalhousie University conducted research on Wistar rats to check the reduction of early stages of inflammation and prevention of nerve damage. The tests included local CBD administration and topical treatment. The results show the inhibition of pain and the establishment of sensation due to local administration. However, topic treatment was shown to reduce leukocyte trafficking and joint hyperemia in the early stages. Nociceptive pain relates to tissue damage picked up by the brain. It includes all types of pain like arthritis, autoimmune diseases like ulcerative colitis, and simple pain like headaches, cramps, etc.

chronic illness

Communication is the key molecularly too, and not just interpersonally. When there is cell damage due to an injury or chronic illness, the body senses it and pumps inflammatory agents on the cells. The main point is to promote apoptosis or the death of that cell. Our bodies don’t like failed cells and prefer to remove it at the correct time to maintain proper functioning of the body and keep away from possible cancers. However, when this turns into a chronic condition, it becomes an inflammatory pain.


Extensive research on CBD oil shows how it manages chronic pain conditions like diabetes, fibromyalgia, multiple sclerosis, etc. According to these, CBD is particularly effective in controlling neuropathic pain, which is a result of peripheral nerve injury.

The activation of the CB2 receptor is useful in the management of chronic pain, which does not mostly respond properly to other treatments. CBD attaches to a particular ECS receptor, which might be useful in restoring the channels that reduce the pain. 

Another way CBD assists in reducing pain is by targeting and then restoring the glycine receptors of the central nervous system. These specific receptors are present in particular parts of the brain and spinal cord and relieve neuropathic and inflammatory pain. Inflammatory components like prostaglandins mostly shut down these receptors, which results in increased pain. However, CBD efficiently reactivates these receptors and helps reduce pain.

Fibromyalgia, a type of chronic pain, is a persistent, ubiquitous pain that arises due to disruption in the central nervous system. According to researchers, deficiency in the endocannabinoid system may be the reason for reduced pain, and sleep and mood variations related to fibromyalgia.

In cases where amplified pain sensitivity stemmed from depression of the endocannabinoid system, CBD lowered pain sensitivity efficiently. Also, according to studies, people with fibromyalgia experienced a great amount of relief from pain, sleep deprivation, mood disorders, anxiety, and stiffness after using cannabinoids.


When using CBD oil, always keep in mind that everyone is different, and the onset time may differ. The standard recommended dosage is 2.5mg to 20mg, twice daily. You can increase the amount you take every 3-4 weeks until you feel relief in the symptoms. Don’t forget to reduce the intake if the symptoms worsen. CBD gummies are also beneficial in managing such persistent pain. Visit this site to know more about CBD Gummies benefits. Check out, you can get all the information about which of the two works best for you.

It is advisable to keep a daily track of your intake as it will help you to narrow down on what makes you feel better.


Recent research reveals a synergizing effect between omega-3 fatty acids like EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), and CBD. These anti-inflammatory and pain-relieving properties, when merged, offer a better comprehensive effect on the central nervous system to reduce chronic pain. Several doctors now recommend this mixture to their patients.


If you want a great CBD oil for chronic pain related issues, consult your doctor or a verified herbalist who can help you to their best potential. Cannabidiol is non-intoxicating and has a host of other therapeutic benefits. Apart from alleviating chronic pain, other benefits of CBD include relieving stress and anxiety, treating sleep deprivation, and helping in cancer treatment, among others.

It also has no side effects, which is quite common in the traditional painkillers. It doesn’t matter if it comes from medical marijuana or hemp; CBD has proven to be successful in controlling and relieving pain in several medical conditions.

In light of the increasing body of scientific and informal information, there is a lot of hope for future treatment of chronic pain, inflammation, and other nervous systems related issues. The failure of medical drugs in certain fields and the success of CBD in those fields is the reason why it won the hearts of so many people around the world.

Hopefully, there will be numerous thorough researches in the future to know more about the relationship between chronic pain management and CBD. There is more to the cannabis plant than what meets the eye.



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